Condition · ICD-10 F32.9
Depression
Major Depressive Disorder
A mood disorder causing persistent sadness, loss of interest, and impaired daily functioning.
Major depressive disorder is one of the most prevalent mental health conditions worldwide, characterized by depressed mood, anhedonia, sleep disturbances, and cognitive impairment. It has a multifactorial etiology involving genetic, neurobiological, and psychosocial factors. SSRIs are the first-line pharmacological treatment due to their efficacy and tolerability profile.
At a glance
Medications tracked
10
First-line options
Sertraline, Escitalopram, Fluoxetine, Duloxetine, Escitalopram, Fluoxetine, Sertraline
Related conditions
Anxiety DisorderBipolar DisorderInsomniaPTSD
First-line Related Treatments
Commonly associated primary options — verify with your clinician
Short-term / As-needed
Related options for acute or bridging use
Situational
Related options for specific presentations
Top treatments tried for Depression
Community-driven data · early preview
Sertraline
1,800 people tried
★★★★★4.3
Escitalopram
1,520 people tried
★★★★★4.1
Fluoxetine
1,240 people tried
★★★★★4.0
Duloxetine
960 people tried
★★★★★3.8
Help build the dataset — log treatments you've tried, rate what helped, and report side effects.