Condition · ICD-10 H04.123

Dry Eye Disease

Keratoconjunctivitis Sicca

A chronic condition in which the eyes do not produce enough tears, or produce poor-quality tears, causing irritation, redness, and blurred vision.

Dry eye disease affects an estimated 16 million Americans and is caused by tear film instability, reduced production, or increased evaporation. It is more prevalent in women and older adults. Artificial tears are first-line; anti-inflammatory topical agents (cyclosporine, lifitegrast) are indicated for chronic dry eye disease with inflammation.

At a glance
Medications tracked
5
First-line options
Artificial Tears, Carboxymethylcellulose
Related conditions
Sjögren's SyndromeRheumatoid ArthritisLupusBlepharitis

First-line Related Treatments

Commonly associated primary options — verify with your clinician

Primary options
Artificial Tears
Artificial Tears
OTC
Drops
Strength 0.5%
NDC 0998-0058-15
Carboxymethylcellulose
Carboxymethylcellulose
OTC
Drops
Strength 0.5%
NDC 0023-4210-15

Short-term / As-needed

Related options for acute or bridging use

Acute or bridging use
Cyclosporine Ophthalmic
Cyclosporine Ophthalmic
Rx
Emulsion
Strength 0.05%
NDC 0023-9163-05
Lifitegrast Ophthalmic
Lifitegrast Ophthalmic
Rx
Solution
Strength 5%
NDC 50004-0001-01

Situational

Related options for specific presentations

Specific presentations
Hydroxypropyl Cellulose
Hydroxypropyl Cellulose
Rx
Insert
Strength 5 mg
NDC 0023-4820-00

Top treatments tried for Dry Eye Disease

Community-driven data · early preview

Artificial Tears
1,800 people tried
4.3
Carboxymethylcellulose
1,520 people tried
4.1
Cyclosporine Ophthalmic
1,240 people tried
4.0
Lifitegrast Ophthalmic
960 people tried
3.8
Help build the dataset — log treatments you've tried, rate what helped, and report side effects.