Condition · ICD-10 N30.10

Interstitial Cystitis

Painful Bladder Syndrome

A chronic bladder condition causing recurring pelvic pain, pressure, and an urgent need to urinate frequently.

Interstitial cystitis is a chronic bladder pain disorder with unknown etiology, disproportionately affecting women. It significantly impairs quality of life. Management is multimodal: dietary modification to avoid bladder irritants, physical therapy, oral medications (pentosan polysulfate, tricyclic antidepressants), and bladder instillations in refractory cases.

At a glance
Medications tracked
5
First-line options
Pentosan Polysulfate, Amitriptyline
Related conditions
EndometriosisPCOSUrinary Tract InfectionFibromyalgia

First-line Related Treatments

Commonly associated primary options — verify with your clinician

Primary options
Pentosan Polysulfate
Pentosan Polysulfate
Rx
Capsule
Strength 100 mg
NDC 0025-0196-60
Amitriptyline
Amitriptyline
Rx
Tablet
Strength 25 mg
NDC 0093-0102-01

Short-term / As-needed

Related options for acute or bridging use

Acute or bridging use
Hydroxyzine Hydrochloride
Hydroxyzine Hydrochloride
Rx
Tablet
Strength 25 mg
NDC 0093-5061-01
Phenazopyridine
Phenazopyridine
OTC
Tablet
Strength 100 mg
NDC 0536-4489-01

Situational

Related options for specific presentations

Specific presentations
Cimetidine
Cimetidine
OTC
Tablet
Strength 400 mg
NDC 0182-0523-60

Top treatments tried for Interstitial Cystitis

Community-driven data · early preview

Pentosan Polysulfate
1,800 people tried
4.3
Amitriptyline
1,520 people tried
4.1
Hydroxyzine Hydrochloride
1,240 people tried
4.0
Phenazopyridine
960 people tried
3.8
Help build the dataset — log treatments you've tried, rate what helped, and report side effects.