Condition · ICD-10 G20

Parkinson's Disease

Progressive Neurological Disorder

A progressive neurological disorder causing tremor, stiffness, and slowed movement due to loss of dopamine-producing neurons.

Parkinson's disease results from degeneration of dopaminergic neurons in the substantia nigra. Motor symptoms include resting tremor, rigidity, bradykinesia, and postural instability. Levodopa-carbidopa remains the most effective symptomatic treatment; dopamine agonists and MAO-B inhibitors are alternatives for early disease or adjuncts in advanced stages.

At a glance
Medications tracked
7
First-line options
Carbidopa-Levodopa, Carbidopa-Levodopa ER, Pramipexole Dihydrochloride, Ropinirole Hydrochloride
Related conditions
Alzheimer's DiseaseEssential TremorLewy Body DementiaMultiple System Atrophy

First-line Related Treatments

Commonly associated primary options — verify with your clinician

Primary options
Carbidopa-Levodopa
Carbidopa-Levodopa
Rx
Tablet
Strength 25 mg-100 mg
NDC 0603-2456-21
Carbidopa-Levodopa ER
Carbidopa-Levodopa ER
Rx
Tablet
Strength 50 mg-200 mg
NDC 0093-0647-01
Pramipexole Dihydrochloride
Pramipexole Dihydrochloride
Rx
Tablet
Strength 0.5 mg
NDC 0093-0090-01
Ropinirole Hydrochloride
Ropinirole Hydrochloride
Rx
Tablet
Strength 1 mg
NDC 0173-0697-55

Short-term / As-needed

Related options for acute or bridging use

Acute or bridging use
Selegiline
Selegiline
Rx
Tablet
Strength 5 mg
NDC 0037-4801-10

Situational

Related options for specific presentations

Specific presentations
Entacapone
Entacapone
Rx
Tablet
Strength 200 mg
NDC 0078-0469-05
Amantadine Hydrochloride
Amantadine Hydrochloride
Rx
Capsule
Strength 100 mg
NDC 0574-0118-01

Top treatments tried for Parkinson's Disease

Community-driven data · early preview

Carbidopa-Levodopa
1,800 people tried
4.3
Carbidopa-Levodopa ER
1,520 people tried
4.1
Pramipexole Dihydrochloride
1,240 people tried
4.0
Ropinirole Hydrochloride
960 people tried
3.8
Help build the dataset — log treatments you've tried, rate what helped, and report side effects.