Condition · ICD-10 E28.2

PCOS

Polycystic Ovary Syndrome

A hormonal disorder causing enlarged ovaries with small cysts, irregular periods, excess androgen, and metabolic disturbances.

Polycystic ovary syndrome is the most common endocrine disorder in women of reproductive age, affecting 6–12% of this population. It involves insulin resistance, hyperandrogenism, and ovulatory dysfunction. Treatment is symptom-directed: combined oral contraceptives for menstrual irregularity and androgen excess, metformin for insulin resistance, and ovulation induction agents for fertility.

At a glance
Medications tracked
6
First-line options
Metformin, Spironolactone
Related conditions
EndometriosisType 2 DiabetesObesityHypothyroidism

First-line Related Treatments

Commonly associated primary options — verify with your clinician

Primary options
Metformin
Metformin
Rx
Tablet
Strength 500 mg
NDC 0378-6000-91
Spironolactone
Spironolactone
Rx
Tablet
Strength 50 mg
NDC 0025-1025-31

Short-term / As-needed

Related options for acute or bridging use

Acute or bridging use
Clomiphene Citrate
Clomiphene Citrate
Rx
Tablet
Strength 50 mg
NDC 0062-3401-03
Norethindrone
Norethindrone
Rx
Tablet
Strength 0.35 mg
NDC 0536-4784-01

Situational

Related options for specific presentations

Specific presentations
Etonogestrel-Ethinyl Estradiol
Etonogestrel-Ethinyl Estradiol
Rx
Ring
Strength 0.12 mg/0.015 mg
NDC 0052-0273-01
Finasteride
Finasteride
Rx
Tablet
Strength 5 mg
NDC 0093-7244-56

Top treatments tried for PCOS

Community-driven data · early preview

Metformin
1,800 people tried
4.3
Spironolactone
1,520 people tried
4.1
Clomiphene Citrate
1,240 people tried
4.0
Norethindrone
960 people tried
3.8
Help build the dataset — log treatments you've tried, rate what helped, and report side effects.