Condition · ICD-10 K27.9

Peptic Ulcer Disease

Gastric and Duodenal Ulcers

Open sores that develop on the inner lining of the stomach or upper small intestine, often caused by H. pylori infection or NSAID use.

Peptic ulcer disease is primarily caused by Helicobacter pylori infection and chronic NSAID use. H. pylori eradication with triple or quadruple antibiotic therapy is curative for H. pylori-associated ulcers. Proton pump inhibitors promote ulcer healing and are essential in management. NSAID cessation is critical when applicable.

At a glance
Medications tracked
7
First-line options
Omeprazole, Pantoprazole
Related conditions
GERDGastritisHelicobacter Pylori InfectionStomach Cancer

First-line Related Treatments

Commonly associated primary options — verify with your clinician

Primary options
Omeprazole
Omeprazole
OTC
Capsule
Strength 20 mg
NDC 0115-0576-01
Pantoprazole
Pantoprazole
Rx
Tablet
Strength 40 mg
NDC 0093-3036-56

Short-term / As-needed

Related options for acute or bridging use

Acute or bridging use
Amoxicillin
Amoxicillin
Rx
Capsule
Strength 500 mg
NDC 0093-3109-05
Clarithromycin
Clarithromycin
Rx
Tablet
Strength 500 mg
NDC 0074-3368-60
Metronidazole
Metronidazole
Rx
Tablet
Strength 500 mg
NDC 0093-0321-01

Situational

Related options for specific presentations

Specific presentations
Tetracycline
Tetracycline
Rx
Capsule
Strength 500 mg
NDC 0115-4027-01
Bismuth Subsalicylate
Bismuth Subsalicylate
OTC
Tablet
Strength 262 mg
NDC 0904-0031-40

Top treatments tried for Peptic Ulcer Disease

Community-driven data · early preview

Omeprazole
1,800 people tried
4.3
Pantoprazole
1,520 people tried
4.1
Amoxicillin
1,240 people tried
4.0
Clarithromycin
960 people tried
3.8
Help build the dataset — log treatments you've tried, rate what helped, and report side effects.