Condition · ICD-10 G25.81

Restless Legs Syndrome

RLS

A neurological condition causing an uncontrollable urge to move the legs, usually worse at night and during rest.

Restless legs syndrome (RLS) is characterized by uncomfortable sensations in the legs and an urge to move them, typically worsening at rest and in the evening. Dopamine agonists are first-line for moderate to severe RLS; addressing iron deficiency is important as a secondary cause.

At a glance
Medications tracked
4
First-line options
Rotigotine
Related conditions
Periodic Limb Movement DisorderPeripheral NeuropathyIron Deficiency AnemiaFibromyalgia

First-line Related Treatments

Commonly associated primary options — verify with your clinician

Primary options
Rotigotine
Rotigotine
Rx
Patch
Strength 3 mg/24h
NDC 50474-0803-03

Short-term / As-needed

Related options for acute or bridging use

Acute or bridging use
Clonazepam
Clonazepam
Rx
Tablet
Strength 2 mg
NDC 43063-0788-30

Situational

Related options for specific presentations

Specific presentations
Carbamazepine
Carbamazepine
Rx
Tablet
Strength 200 mg
NDC 70518-2841-00
Carbamazepine er
Carbamazepine er
Rx
Tablet
Strength 200 mg
NDC 62135-0928-60

Top treatments tried for Restless Legs Syndrome

Community-driven data · early preview

Rotigotine
1,800 people tried
4.3
Clonazepam
1,520 people tried
4.1
Help build the dataset — log treatments you've tried, rate what helped, and report side effects.