Ulcerative Colitis

Inflammatory Bowel Disease

A chronic inflammatory bowel disease causing inflammation and ulcers in the lining of the colon and rectum.

Ulcerative colitis is limited to the colon and rectum, presenting with bloody diarrhea, urgency, and cramping. Disease severity guides treatment: mesalamine for mild disease, corticosteroids for moderate flares, and biologics or JAK inhibitors for moderate-to-severe disease not responding to conventional therapy. Colectomy is curative.