Leg Cramps

Muscle Cramps / Charley Horse

Mild severity65% reported by patientsICD-10: R25.2

Summary

Sudden, involuntary muscle contractions in the leg — most often in the calf — that cause intense pain lasting seconds to minutes.

What is it?

Leg cramps are sudden, painful, involuntary contractions of a muscle or muscle group — most commonly the calf (gastrocnemius). They affect up to 60% of adults and are particularly common at night (nocturnal leg cramps), disrupting sleep. Most are idiopathic (no clear cause) or related to dehydration, electrolyte imbalance, and prolonged sitting or standing. Secondary causes include medications (diuretics, statins), peripheral artery disease, and nerve compression. Distinguishing nocturnal leg cramps from restless leg syndrome (RLS) is important — RLS causes an urge to move rather than a painful contraction.

Common causes

Lifestyle / Physiological

  • Dehydration
  • Prolonged standing or sitting
  • Exercise (especially in heat)
  • Pregnancy

Electrolyte Imbalance

  • Low magnesium
  • Low potassium
  • Low calcium
  • Low sodium

Medications

  • Diuretics (deplete electrolytes)
  • Statins
  • Beta-agonists
  • Raloxifene
  • Donepezil

Medical Conditions

  • Peripheral artery disease
  • Lumbar spinal stenosis
  • Diabetes
  • Liver cirrhosis
  • Hypothyroidism

When to see a doctor

  • 1Frequent or severe cramps disrupting sleep every night
  • 2Cramps accompanied by significant leg swelling, redness, or skin changes
  • 3Leg pain and cramping that occurs with walking and resolves with rest (claudication — possible arterial disease)
  • 4Cramps with progressive muscle weakness
  • 5Cramps in someone taking diuretics or statins — electrolyte or drug-related
  • 6Cramps in pregnancy — rule out DVT if leg is also swollen

What you can do

  • Stretch the calf before bed: stand and lean against a wall with the back knee straight
  • Stay well hydrated throughout the day, especially during exercise
  • Ensure adequate magnesium through diet (nuts, seeds, leafy greens) or supplements
  • During a cramp: stand on the affected leg, flex the foot upward, and walk it off
  • Warm the muscle after a cramp with a heating pad to reduce residual soreness
  • Reduce caffeine and alcohol, which promote dehydration and electrolyte imbalance

Frequently asked questions

This page is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified health provider with questions about your symptoms or medical conditions.

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