Moderate severity72% reported by patientsICD-10: N95.1
Summary
Sudden episodes of intense heat, sweating, and flushing — most commonly associated with menopause, though other conditions and medications can also cause them.
What is it?
Hot flashes (hot flushes) are sudden episodes of intense warmth spreading over the upper body and face, often followed by sweating, flushing, and sometimes chills. They are the hallmark vasomotor symptom of menopause, affecting up to 80% of women. They result from a narrowed thermoregulatory zone in the hypothalamus, caused by declining estrogen, which triggers inappropriate heat-dissipating responses. The average duration of vasomotor symptoms is 7 years; some women experience them for over a decade. Non-menopausal causes include hormone therapy withdrawal, certain medications, carcinoid tumors, and pheochromocytoma.
Common causes
Hormonal
Menopause and perimenopause
Surgical menopause (oophorectomy)
Breast cancer hormone therapy (tamoxifen, aromatase inhibitors)
Male androgen deprivation therapy
Medications
SSRIs / SNRIs (paradoxically can also treat hot flashes)
Opioid withdrawal
Nifedipine
Calcitonin
Medical Conditions
Carcinoid syndrome
Pheochromocytoma
Hyperthyroidism
Lymphoma (paraneoplastic)
When to see a doctor
1Hot flashes that occur more than 7–10 times per day or significantly disrupt sleep
2Hot flashes in a man or a premenopausal woman without explanation
3Hot flashes with hypertension, palpitations, and headache (pheochromocytoma)
4Hot flashes with diarrhea, facial flushing, and wheezing (carcinoid syndrome)
5Hot flashes after starting or stopping a medication
6Vasomotor symptoms causing significant distress or quality-of-life impairment
What you can do
✓Layer clothing so you can quickly remove layers during a flash
✓Keep a small fan at your desk and bedside
✓Avoid triggers: caffeine, alcohol, spicy food, hot beverages, stress, and hot environments
✓Cool your bedroom to 65–68°F (18–20°C) with moisture-wicking bedding
This page is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified health provider with questions about your symptoms or medical conditions.
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