Mild severity40% reported by patientsICD-10: F52.0
Summary
Persistent reduction in sexual desire that causes personal distress, arising from hormonal, psychological, relational, or medication-related causes.
What is it?
Hypoactive sexual desire disorder (HSDD) is defined as persistently low or absent sexual desire causing personal distress. It is the most common female sexual complaint — affecting up to 40% of women at some point — and is also prevalent in men (15–25%), particularly those with low testosterone or depression. Major causes include low testosterone (both sexes), menopause and estrogen deficiency, hypothyroidism, depression, anxiety, relationship factors, and medications (notably SSRIs, antihypertensives, and hormonal contraceptives). Thorough evaluation considers hormonal, psychological, and relational factors before treatment.
Common causes
Hormonal
Low testosterone (both sexes)
Menopause / low estrogen
Hypothyroidism
Hyperprolactinemia
Postpartum hormonal changes
Psychological
Depression
Anxiety
PTSD / trauma history
Poor body image
Performance anxiety
Medication-Induced
SSRIs / SNRIs
Antihypertensives (beta-blockers)
Hormonal contraceptives
Opioids
Finasteride
Antiandrogens
Relational / Lifestyle
Relationship conflicts
Fatigue / poor sleep
Chronic illness
Alcohol use disorder
When to see a doctor
1Sudden onset low libido — rule out hypothyroidism, hyperprolactinemia, or testosterone deficiency
2Low libido causing significant personal distress or relationship strain
3Associated with symptoms of depression — depression is highly treatable
4Men with low libido, fatigue, and loss of morning erections — check serum testosterone
5Women with low libido after starting a new hormonal contraceptive
What you can do
✓Address sleep and fatigue — inadequate sleep significantly suppresses libido
✓Regular aerobic exercise improves testosterone levels and mood
✓Reduce alcohol — chronic use suppresses testosterone and worsens depression
✓Couples counseling or sex therapy addresses relational and psychological components
✓If a medication is suspected, discuss alternatives with your prescriber before stopping
This page is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified health provider with questions about your symptoms or medical conditions.
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